Chapter 1 The Biology and Genetics of Cells and Organisms ..... 1
Chapter 2 The Nature of Cancer ............................... 25
Chapter 3 Tumor Viruses ...................................... 57
Chapter 4 Cellular Oncogenes ................................. 91
Chapter 5 Growth Factors and Their Receptors ................ 119
Chapter 6 Cytoplasmic Signaling Circuitry Programs Many of
the Traits of Cancer .............................. 159
Chapter 7 Tumor Suppressor Genes ............................ 209
Chapter 8 pRh and Control of the Cell Cycle Clock ........... 255
Chapter 9 p53 and Apoptosis: Master Guardian and
Executioner ....................................... 307
Chapter 10 Eternal Life: Cell Immortalization and
Tumorigenesis ..................................... 357
Chapter 11 Multistep Tumorigenesis ........................... 399
Chapter 12 Maintenance of Genomic Integrity and
the Development of Cancer ......................... 463
Chapter 13 Dialogue Replaces Monologue: Heterotypic
Interactions and the Biology of Angiogenesis ...... 527
Chapter 14 Moving Out: Invasion and Metastasis ............... 587
Chapter 15 Crowd Control: Tumor Immunology and
Immunotherapy ..................................... 655
Chapter 16 The Rational Treatment of Cancer .................. 725
Abbreviations ..................................... A:1
Glossary .......................................... G:1
Index ............................................. I:1
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