Поступления иностранных книг в библиотеки ННЦ в 2003 г.
Институт биоорганической химии |  |
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Phospholipid signaling protocols / Ed. by Bird I.M. - Totowa: Humana, 1998. - XII, 380 p.: ill. - (Methods in molecular biology; Vol. 105). - Протоколы фосфолипидного сигнализирования (мониторинга).
Оглавление
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- This book attempts to summarize for the newcomer to this field those methodological protocols that allow monitoring of the major lipid- and phospholipid-derived second messenger pathways, as well as some additional physiologically important enzymes (the phosphoinositide kinases) involved in further regulating pathway activity. The book in particular covers the investigation of the hormone-sensitive phosphoinositidase C pathway, which gives rise to the formation of inositol 1,4,5-trisphosphate and diacylglycerol, each implicated in the release of intracellular Ca super(2+) and in the activation of protein kinase C, respectively. In addition, the assay of other phospholipases C to yield diacylglycerol from such phospholipids as phosphatidylcholine and phosphatidylethanolamine are described, together with assay of phospholipase A sub(2) and diacylglycerol/monoacylglycerol lipase activity to yield free arachidonate and its metabolites.
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