Statistical approaches to gene - environment interactions for complex phenotypes / ed. by M.Windle. - Cambridge; London: MIT press, 2016. - viii, 296 p.: ill., tab. - Bibliogr. at the end of the chapters. - Ind.: p.283-296. - ISBN 978-0-262-03468-5 Шифр: (И/Е0-S81) 02  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Preface ....................................................... vii 1 Introduction and Overview of Statistical Approaches to Gene × Environment Interactions for Complex Phenotypes ....... 1 Michael Windle 2 Two-Stage Procedures for the Identification of Gene x Environment and Gene × Gene Interactions in Genome-Wide Association Studies ......................................... 11 Charles Kooperberg, James Y. Dai, and Li Hsu 3 Marker-Set Approaches for Assessing Gene × Environment Interactions at Gene Level .................................. 35 Jung-Ying Tzeng and Arnab Maity 4 Set-Based Gene × Environment Interaction Tests for Complex Diseases with Application to Genome-Wide Association and Sequencing Studies .......................................... 53 Shuo Jiao 5 A Gene-Based Approach for Testing Gene × Gene and Gene x Environment Interactions .................................... 71 Tao Wang 6 An Overview of the RELIEF Algorithm and Advancements ........ 95 Alexandre Todorov 7 Gene × Environment Interaction in Obesity: The Contribution of Randomized Clinical Trials ................. 117 Jeanne M. McCaffery and Caroline Y. Doyle 8 Statistical Strategies for Modeling Gene × Environment Interactions in Longitudinal Cohort Studies ................ 147 Bhramar Mukherjee, Yin-Hsiu Chen, Yi-An Ко, Zihuai He, Seunggeun Lee, Min Zhang, and Sung Kyun Park 9 Cumulative Gene × Environment Influences on Neurobehavioral Development in Humans and Nonhuman Primates ................................................... 193 Fatima Umber Ahmed and Erin Loraine Kinnally 10 Complex Phenotypes and the Use of Polygenic Scores to Investigate Gene × Environment Interactions for Substance Use ........................................................ 219 Michael Windle 11 A Statistical Framework for Mediation in Environmental Epigenetics ................................................ 251 Duncan C. Thomas Contributors .................................................. 281 Index ......................................................... 283