Aknowledgments ................................................ vii
Introduction .................................................... 1
ONE
Failing to Define Failure ....................................... 7
TWO
Fail Better: Advice from Samuel Beckett ........................ 25
THREE
The Scientific Basis of Failure ................................ 39
FOUR
The Unreasonable Success of Failure ............................ 49
FIVE
The Integrity of Failure ....................................... 63
SIX
Teaching Failure ............................................... 71
SEVEN
The Arc of Failure ............................................. 97
EIGHT
The Scientific Method of Failure .............................. 119
NINE
Failure in the Clinic ......................................... 135
TEN
Negative Results: How to Love Your Data When It's Wrong ....... 145
ELEVEN
Philosopher of Failure ........................................ 167
TWELVE
Funding Failure ............................................... 177
THIRTEEN
Pharma Failure ................................................ 205
FOURTEEN
A Plurality of Failures ....................................... 215
FIFTEEN
Coda .......................................................... 247
Notes and Wor\s Consulted ..................................... 253
Index ......................................................... 275
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