1 Immunohistochemistry: Overview, Its Potential, and
Challenges ................................................... 1
Syed A. Aziz and Rekha Mehta
2 Tissue Microarray Technology and Its Potential Applications
in Toxicology and Toxicological Immunohistochemistry ......... 5
Ali Mobasheri
3 Importance of Fluorescent In Situ Hybridization in Rodent
Tumors ...................................................... 21
Ana Mendes-da-Silva, Filomena Adega, and Raquel Chaves
4 Quantitation of Immunohistochemistry by Image Analysis
Technique ................................................... 51
Klaus Kayser and Gian Kayser
5 Immunohistochemistry in the Study of Cancer Biomarkers
for Oncology Drug Development ............................... 73
Fang Jiang and Evelyn M. McKeegan
6 Male Reproductive Toxicology and the Role of
Immunohistochemistry ........................................ 95
Daniel G. Cyr
7 Immunohistochemistry and Female Reproductive Toxicology:
The Ovary and Mammary Glands ............................... 113
Daniel G. Cyr, Patrick J. Devine, and Isabelle Plante
8 Immunohistochemistry on Rodent Circulatory System:
Its Possible Use in Investigating Hypertension ............. 147
Chun-Yi Ng, Yusof Kamisah, and Kamsiah Jaarin
9 Role of Lymphoid/Mucosa-Associated Lymphoid Tissue
Markers in Toxicological Immunohistochemistry .............. 179
Kuldeep Singh, E. Driskell, and A. Stern
10 Bone Marker and Immunohistochemistry Changes in Toxic
Environments ............................................... 193
Ahmad Nazrun Shuid, Isa Naina Mohamed, Norliza Muhammad,
Elvy Suhana Mohd Ramli, and Norazlina Mohamed
11 Biomarkers of Skeletal Muscle Injury in the Rat ............ 215
Nivaldo A. Parizotto, Natalia C. Rodrigues, Paulo Sergio
Bossini, and Michael R. Hamblin
Index ......................................................... 227
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