Series Preface .................................................. v
Overview ...................................................... vii
Part I Basic Concepts
1 Extracellular and Intracellular Recordings ................... 3
Nicholas Graziane and Yan Dong
2 Electrical Theory ........................................... 17
Nicholas Graziane and yan Dong
3 Amplifiers .................................................. 33
Nicholas Graziane and Yan Dong
4 Salt Environment ............................................ 55
Nicholas Graziane and Tan Dong
5 Patch Pipettes (Micropipettes) .............................. 69
Nicholas Graziane and Yan Dong
6 Spatiotemporal Effects of Synaptic Current .................. 79
Nicholas Graziane and Yan Dong
7 Perforated Patch ............................................ 91
Nicholas Graziane and Yan Dong
Part II Recording of Synaptic Current
8 Isolation of Synaptic Current .............................. 101
Nicholas Graziane and Yan Dong
9 Fast and Slow Synaptic Currents ............................ 111
Nicholas Graziane and Yan Dong
10 Measuring Kinetics of Synaptic Current ..................... 121
Nicholas Graziane and Yan Dong
11 Measuring Presynaptic Release Probability .................. 133
Nicholas Graziane and Yan Dong
12 Long-Term Measurements ..................................... 145
Nicholas Graziane and Yan Dong
13 Measuring Reversal Potentials .............................. 157
Nicholas Graziane and Yan Dong
Part III Basic Experimentations of Synaptic Transmission
14 Amplitude .................................................. 165
Nicholas Graziane and Yan Dong
15 Pre vs. Post synaptic Effect ............................... 175
Nicholas Graziane and Yan Dong
16 Run-Up and Run-Down ........................................ 187
Nicholas Graziane and Yan Dong
17 Kinetics of Synaptic Current ............................... 193
Nicholas Graziane and Yan Dong
Part IY Experimentations with Computational Components
18 Measurement of a Single Synapse ............................ 209
Nicholas Graziane and Yan Dong
19 Measurement of Silent Synapses ............................. 217
Nicholas Graziane and Yan Dong
20 Dendritic Patch ............................................ 225
Nicholas Graziane and Yan Dong
Part V Experimentations with Molecular and Visual Components
21 Electrophysiological and Visual Tags ....................... 235
Nicholas Graziane and Yan Dong
Part VI In Vivo Recordings
22 Extracellular Recordings ................................... 249
Nicholas Graziane and Yan Dong
Index ......................................................... 259
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