1 Introduction to the Complexity of Cell Surface and
Tissue Matrix Glycoconjugates ................................ 1
Veer P. Bhavanandan and D. Channe Gowda
2 Introduction to Cells Comprising the Nervous System ......... 33
Douglas G. Peters and James R. Connor
3 Synthesis, Processing, and Function of N-glycans in
N-glycoproteins ............................................. 47
Erhard Bieberich
4 Synthesis of O-Linked Glycoconjugates in the Nervous
System ...................................................... 71
Jin-Ichi Inokuchi, Shinji Go, and Yoshio Hirabayashi
5 Chemistry and Function of Glycosaminoglycans in the Nervous
System ...................................................... 89
Nancy B. Schwartz and Miriam S. Domowicz
6 Use of Glycan-Targeted Antibodies/Lectins to Study the
Expression/Function of Glycosyltransferases in the Nervous
System ..................................................... 117
Yasuhiko Kizuka, Kenji Kanekiyo, Shinobu Kitazume, and
Naoyuki Taniguchi
7 From Mass Spectrometry-Based Glycosylation Analysis
to Glycomics and Glycoproteomics ........................... 129
Kay-Hooi Khoo
8 Structural Analysis of Oligosaccharides and
Glycoconjugates Using NMR .................................. 165
Yoshiki Yamaguchi, Takumi Yamaguchi, and Koichi Kato
9 Glycolipid and Glycoprotein Expression During Neural
Development ................................................ 185
Robert K. Yu and Yutaka Itokazu
10 Gangliosides and Cell Surface Ganglioside Glycohydrolases
in the Nervous System ...................................... 223
Massimo Aureli, Maura Samarani, Valentina Murdica, Laura
Mauri, Nicoletta Loberto, Rosaria Bassi, Alessandro
Prinetti, and Sandro Sonnino
11 Role of Myelin-Associated Glycoprotein (Siglec-4a) in
the Nervous System ......................................... 245
Pablo H.H. Lopez
12 Role of Galactosylceramide and Sulfatide in
Oligodendrocytes and CNS Myelin: Formation of
a Glycosynapse ............................................. 263
Joan M. Boggs
13 Glycosignaling: A General Review ........................... 293
Glyn Dawson
14 Glycosphingolipids in the Regulation of the Nervous
System ..................................................... 307
Koichi Furukawa, Yusuke Ohmi, Yuki Ohkawa, Orie Tajima,
and Keiko Furukawa
15 Glycobiology of Ion Transport in the Nervous System ........ 321
Martha C. Nowycky, Gusheng Wu, and Robert W. Ledeen
16 O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal
Functions and in Neurodegeneration ......................... 343
Olof Lagerlöf and Gerald W. Hart
17 N-Glycosylation in Regulation of the Nervous System ........ 367
Hilary Scott and Vladislav M. Panin
18 Roles of Carbohydrates in the Interaction of Pathogens
with Neural Cells .......................................... 395
Cara-Lynne Schengrund
19 Glycoconjugate Changes in Aging and Age-Related Diseases ... 415
Susumu Ando
20 Gangliosides and Glycolipids in Neurodegenerative
Disorders .................................................. 449
J.S. Schneider
21 Glycosidases: Inborn Errors of Glycosphingolipid
Catabolism ................................................. 463
Hisashi Ashida and Yu-Teh Li
22 Ganglioside Storage Diseases: On the Road to Management .... 485
Thomas N. Seyfried, Hannah E. Rockwell, Karie A.
Heinecke, Douglas R. Martin, and Miguel Sena-Esteves
23 Dynamic Aspects of Neural Tumor Gangliosides ............... 501
Stephan Ladisch and Yihui Liu
24 Galectins and Neuroinflammation ............................ 517
Hung-Lin Chen, Fang Liao, Teng-Nan Lin, and Fu-Tong Liu
25 Glycoconjugates and Neuroimmunological Diseases ............ 543
Hugh J. Willison
Index ......................................................... 567
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