Genomic applications in pathology / eds.: G.J.Netto, I.Schrijver. - New York: Springer Science+Business Media, 2015. - xv, 622 p.: ill., tab. - Bibliogr. at the end of the chapters. - Ind.: p.605-622. - ISBN 978-1-4939-0726-7 Шифр: (И/Р25-G36) 02  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Part I Genomic Technologies 1 Current Massively Parallel Sequencing Technologies: Platforms and Reporting Considerations ....................... 3 John R. ten Bosch, Waytve Grody 2 Emerging Next-Generation Sequencing Technologies ............ 19 Matthew W. Anderson 3 Transcriptome Sequencing (RNA-Seq) .......................... 31 Sugganth Daniel, Alberto Paniz-Mondolfi, Federico A. Monzon 4 MiRNA Expression Assays ..................................... 45 Cornelia Braicu, Beatriz M. Maia, Ioana Berindan-Neagoe, George A. Calin 5 Circulating Tumor Cells: Enrichment and Genomic Applications ................................................ 71 Marija Balic, Richard J. Cote 6 Circulating Cell-Free DNA for Molecular Diagnostics and Therapeutic Monitoring ...................................... 85 Julia A. Beaver, Ben H. Park Part II Practice Related Aspects of Clinical Genomics 7 Genomic Pathology: Training for New Technology ............. 101 Richard L. Haspel 8 Implementation of Genome Sequencing Assays ................. 111 Joshua L. Deignan 9 Regulatory and Reimbursement Issues in Genomic Testing ..... 119 Jan A. Nowak 10 Patents and Proprietary Assays ............................. 129 Roger D. Klein 11 Ethical Issues in Clinical Genetics and Genomics ........... 141 Henry T. Greely Part III Clinical Implementation of Diagnostic Genomics 12 Transitioning Discoveries from Cancer Genomics Research Laboratories into Pathology Practice ....................... 159 Tamara Jamaspishvili, Jeremy A. Squire 13 Bioinformatics Tools in Clinical Genomics .................. 177 David K. Crockett, Karl V. Voelkerding 14 Next Generation Sequencing for Single-Gene Analysis ........ 197 Hao Ho, Christopher D. Gocke 15 Next-Generation Sequencing for Gene Panels ................. 209 Michael O. Dorschner 16 Implementation of Exome Sequencing Assay ................... 225 Arunkanth Ankala, Madhuri R. Hegde 17 Implementation of Genome Sequencing Assays ................. 241 Tina M. Hambuch, Carri-Lyn Mead 18 Clinical Information Systems in the Era of Personalized Medicine ................................................... 259 Jonathan Nowak, Lynn Bry 19 Reporting Clinical Genomic Assay Results and the Role of the Pathologist ............................................ 277 Janina A. Longtine Part IV Genomic Applications in Oncology 20 Genomic Applications in Hematologic Oncology ............... 297 Kevin E. Fisher, Charles E. Hill 21 Genomic Applications in Brain Tumors ....................... 321 Matija Snuderl 22 Genomic Applications in Head and Neck Cancers .............. 341 Sun M. Ahn, Nishant Agrawal 23 Genomic Applications in Breast Carcinoma ................... 359 Leticia De Mattos-Arruda, Britta Weigelt, Jorge S. Reis-Filhо 24 Genomic Applications in Pulmonary Malignancies ............. 383 Reinhard Büttner, Margarete Odenthal, Sabine Merkelbach- Bruse 25 Genomic Applications in Colorectal and Pancreatic Tumors ... 415 Andreas Jung, Ralph Hruban 26 Molecular Pathology of Genitourinary Cancers: Translating the Cancer Genome to the Clinic ............................ 435 Joshua I. Warrick, Scott A. Tomlins 27 Genomic Applications in Gynecologic Malignancies ........... 465 Sarah Chiang, Luciano G. Martelotto, Britta Weigelt 28 Genomic Applications in Epithelial Ovarian Malignancies .... 489 James D. Brenton 29 Genomic Applications in Soft Tissue Sarcomas ............... 503 Eva Wardelmann, Wolfgang Hartmann Part V Genomic Applications of Inherited and Infectious Diseases 30 Genomic Applications in Inherited Genetic Disorders ........ 535 Bryan L. Krock, Rong Mao, D. Hunter Best, Elaine Lyon 31 Genomic Applications in Pharmacogenomics ................... 553 Rehan Qayyum 32 Sequencing Cell Free DNA in the Maternal Circulation to Screen for Down Syndrome and Other Common Aneuploidies ..... 563 Glenn E. Palomaki 33 Genomic Applications in the Clinical Management of Infectious Diseases ..................................... 581 Martina I. Lefterova, Niaz Banaei, Benjamin A. Pinsky Index ......................................................... 605