Mass spectrometry in metabolomics: methods and protocols / ed. by D.Raftery. - New York: Humana press, 2014. - xvi, 360 p.: ill., tab. - (Methods in molecular biology; 1198) (Springer protocols). - Bibliogr. at the end of the chapters. - Ind.: p.355-360. - ISBN 978-1-4939-1257-5; ISSN 1064-3745 Шифр: (Pr 852/1198) 02  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Preface ....................................................... vii Contributors ................................................. xiii Part I Historical and Methodology Overview 1 Overview of Mass Spectrometry-Based Metabolomics: Opportunities and Challenges ................................. 3 G.A. Nagano, Gowda and Danijel Djukovic Part II Global LC-MS Based Metabolic Profiling 2 Global Metabolic Profiling Using Ultra-Performance liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry .. 15 Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai 3 LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations ................................ 29 Camilla B. Hill, Antony Bacic, and Ute Roessner 4 Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry ......................... 43 Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Hél&eagrave;ne Baubichon- Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones 5 Sample Preparation Methods for LC-MS-Based Global Aqueous Metabolite Profiling ........................................ 75 Antoni Beltran, Sara Samino, and Oscar Yanes Part III. Global GC MS and CE-MS Based Metabolic Profiling 6 Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection ............. 83 Luke C. Marney, Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec 7 Analysis of Mouse Liver Metabolites by GC × GC-TOF MS ....... 99 Xue Shi, Xinmin Yin, and Xiang Zhang 8 Metabolite Fingerprinting by Capillary Electrophoresis- Mass Spectrometry .......................................... 107 Antonia Garcia, Shama Naz, and Coral Barbas Part IV Isotope Labeling Methods 9 Quantitative Metabolomic Profiling Using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry ............................................... 127 Ruokun Zhou and Liang Li 10 Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis ................................................... 137 Hans Fredrik Nyvold Kvitvang, Kare A. Kristiansen, Stina K. Lien, and Per Bruheim 11 Stable Isotope-Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS ............................. 147 Richard M. Higashi, Teresa W.-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane Part V Targeted Aqueous Metabolite Profiling 12 Multiplexed, Quantitative, and Targeted Metabolite Profiling by LC-MS/MRM ..................................... 171 Ru Wei, Guodong Li, and Albert B. Seymour Part VI Lipid and Bile Acid Profiling Methods 13 Multidimensional Mass Spectrometry-Based Shotgun Lipidomics ................................................. 203 Miao Wang and Xianlin Han 14 Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics Using High- Resolution Mass Spectrometry ............................... 221 Mojgan Masoodi and Dietrich A. Volmer 15 Ultra-Performance Liquid Chromatography-Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue, and Cultured Cells of Different Species ...... 233 Juan Carlos García-Cañaveras, María Teresa Donate, and Agustín Lahoz Part VII Profiling Volatile Organic Compounds 16 Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry Combined with Chemometric Analysis ....................................... 251 Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten 17 Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs) .......................... 265 Shucha Zhang and Daniel Raftery Part VIII Profiling and Imaging Using Atomospheric Sampling Methods 18 Metabolite Profiling by Direct Analysis in Real-Time Mass Spectrometry .............................................. 275 Christina M. Jones, María Eugenia Monge, and Facundo M. Fernández 19 Analysis of Dried Blood Spots Using DESI Mass Spectrometry ............................................... 291 Justin M. Wiseman and Joseph H. Kennedy 20 DESI-MS Imaging of Lipids and Metabolites from Biological Samples .................................................... 299 Livia S. Eberlin 21 Metabolic Imaging Using NanostructureTnitiator Mass Spectrometry (NIMS) ........................................ 313 Katherine B. Louie and Trent R. Northen Part IX Statistical Analysis Methods 22 Statistical Analysis and Modeling of Mass Spectrometry- Based Metabolomics Data .................................... 333 Bowei Xi, Haiwei Gu, Hamid Baniasadi, and Daniel Raftery Index ......................................................... 355