Preface ....................................................... vii
Microbial Sensing by Toll-Like Receptors and Intracellular
Nucleic Acid Sensors ............................................ 1
Surya Pandey, Taro Kawai, and Shizuo Akira
Emerging Principles Governing Signal Transduction by Pattern-
Recognition Receptors .......................................... 19
Jonathan C. Kagan and Gregory M. Barton
Transcriptional Control of Inflammatory Responses .............. 35
Stephen T. Smale and Gioacchino Natoli
Inflammasomes .................................................. 45
Marcel R. de Zoete, Noah W. Palm, Shu Zhu, and Richard
A. Flavell
Tumor Necrosis Family Superfamily in Innate Immunity and
Inflammation ................................................... 67
John Šedý, Vasileios Bekiaris, and Carl F. Ware
IL-6 in Inflammation, Immunity, and Disease .................... 85
Toshio Tanaka, Masashi Narazaki, and Tadamitsu Kishimoto
The Chemokine System in Innate Immunity ....................... 101
Caroline L. Sokol and Andrew D. Luster
Lipid Mediators in the Resolution of Inflammation ............. 121
Charles N. Serhan, Nan Chiang, Jesmond Dalli, and Bruce
D. Levy
DNA Degradation and Its Defects ............................... 141
Kohki Kawane, Kou Motani, and Shigekazu Nagata
Group 2 Innate Lymphoid Cells in Health and Disease ........... 155
Brian S. Kim and David Artis
Allergic Inflammation—Innately Homeostatic .................... 169
Laurence E. Cheng and Richard M. Locksley
Inflammation and the Blood Microvascular System ............... 183
Jordan S. Pober and William C. Sessa
Sinusoidal Immunity: Macrophages at the Lymphohem-atopoietic
Interface ..................................................... 195
Siamon Gordon, Annette Pluddemann, and Subhankar
Mukhopadhyay
Approaching the Next Revolution? Evolutionary Integration of
Neural and Immune Sensing and Response ........................ 215
Kevin J. Tracey
Index ......................................................... 227
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