1 Extrasynaptic GABAA Receptors ................................ 1
Adam C. Errington
2 Extrasynaptic GABAA Receptors: Subunit Composition,
Distribution, and Regulation ................................ 15
Jean-Marc Fritschy and Patrizia Panzanelli
3 Biophysical Properties of Recombinant γ2- and δ-subunit
Containing GABAA Receptors .................................. 33
Robert L. Macdonald and Emmanuel J. Botzolakis
4 The Pharmacology of Extrasynaptic GABAA Receptors ........... 51
Keith A. Wafford
5 Neurosteroids and Extrasynaptic GABAA Receptors ............. 75
William M. Connelly
6 Sources of GABA That Activate Extrasynaptic GABAA
Receptors ................................................... 85
Damian Bright, Catriona Houston and Stephen Brickley
7 GPCR Modulation of Extrasynapitic GABAA Receptors .......... 125
William M. Connelly, Adam C. Errington, Josue G. Yagüe,
Anna Cavaccini, Vincenzo Crunelli and Giuseppe Di Giovanni
8 Extrasynaptic GABAA Receptors and Tonic Inhibition in
Spinal Cord ................................................ 155
Emanuel Loeza-Alcocer, Carmen Andrés, Justo Aguilar,
Ricardo Felix and Rodolfo Delgado-Lezama
9 The Role of Peri-synaptic GABA Receptors After Stroke ...... 179
Andrew N. Clarkson and Mary Chebib
10 The Role of Extrasynaptic GABAA Receptors in Focal
Epilepsy ................................................... 207
Matthew C. Walker and Ivan Pavlov
11 Gain-of-Function of Thalamic Extrasynaptic GABA-A
Receptors in Typical Absence Seizures ...................... 223
Vincenzo Crunelli, Giuseppe Di Giovanni, H. Rheinallt
Parri and Adam C. Errington
12 GABAergic Control of the Hypothalamic-Pituitary-Adrenal
(HPA) Axis: Role of Extrasynaptic GABAA Receptors .......... 239
Jamie Maguire
13 Tonic GABAA-Receptor-Mediated Inhibition in Fragile-X
Syndrome: A Cause of Dysfunction or a Pathway for a Cure? .. 271
Brandon S. Martin and Molly M. Huntsman
Index ......................................................... 285
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