1 X-Ray Analysis of Prokaryotic and Eukaryotic Ribosomes ....... 1
Lasse В. Jenner, Adam Ben-Shem, Natalia Demeshkina, Marat
Yusupov, and Gulnara Yusupova
2 A Passage Through the Ribosome by Cryo-EM ................... 27
Partha P. Datta and Ananya Chatterjee
3 Molecular Dynamics Simulations of the Ribosome .............. 51
Karissa Y. Sanbonmatsu, Scott C. Blanchard, and Paul
C. Whitford
4 Structural Analyses of the Ribosome by Chemical
Modification Methods ........................................ 69
Jonathan A. Leshin, Arturas Meskauskas, and Jonathan
D. Dinman
5 Methods for Studying the Interactions of Translation
Factors with the Ribosome ................................... 83
Assen Marintchev
6 Riboproteomic Approaches to Understanding IRES Elements .... 103
Encarnacion Martinez-Salas, David Pineiro, and Noemi
Fernandez
7 Rapid Kinetic Analysis of Protein Synthesis ................ 119
Marina V. Rodnina and Wolfgang Wintermeyer
8 Investigating RNAs Involved in Translational Control
by NMR and SAXS ............................................ 141
Kathryn D. Mouzakis, Jordan E. Burke, and Samuel
E. Butcher
9 Analyses of RNA-Ligand Interactions by Fluorescence
Anisotropy ................................................. 173
Aparna Kishor, Gary Brewer, and Gerald M. Wilson
10 Approaches for the Identification and Characterization
of RNA-Protein Interactions ................................ 199
Saiprasad Palusa and Jeffrey Wilusz
11 A Multidisciplinary Approach to RNA Localisation ........... 213
Russell S. Hamilton, Graeme Ball, and Ilan Davis
12 Virtual Screening for RNA-Interacting Small Molecules ...... 235
Hyun-Ju Park and So-Jung Park
13 The "Fifth" RNA Nucleotide: A Role for Ribosomal RNA
Pseudouridylation in Control of Gene Expression
at the Translational Level ................................. 253
Mary McMahon, Cristian Bellodi, and Davide Ruggero
14 Translational Control of Synaptic Plasticity and Memory .... 289
Arkady Khoutorsky, Christos Gkogkas, and Nahum Sonenberg
Index ......................................................... 311
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