Genetic influences on addiction: an international phenotype approach / Massachusets inst. of technology; ed. by J.MacKillop, M.R.Munafo. - Cambridge; London: MIT press, 2013. - x, 386 p.: ill. - Incl. bibl. ref. - Ind.: p.373-386. - ISBN 978-0-262-01969-9  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Contributors ................................................... ix 1 An Intermediate Phenotype Approach to Addiction Genetics ..... 1 James MacKillop and Marcus R. Munafò 2 Electrophysiological Intermediate Phenotypes for the Detection of Genetic Influences on Alcoholism ............... 19 Mary-Anne Enoch 3 Differential Metabolism of Alcohol as an Intermediate Phenotype of Risk for Alcohol Use Disorders: Alcohol and Aldehyde Dehydrogenase Variants ............................. 41 Tamara L. Wall, Susan E. Luczak, Dana Orlowska, and Danielle Pandika 4 Nicotine Metabolism as an Intermediate Phenotype ............ 65 Meghan J. Chenoweth and Rachel F. Tyndale 5 Subjective Responses to Alcohol as an Endophenotype: Implications for Alcoholism Etiology and Treatment Development ................................................. 97 Lara A. Ray and Markus Heilig 6 Subjective Drug Effects as Intermediate Phenotypes for Substance Abuse ............................................ 121 Leah M. Mayo, Abraham A. Palmer, and Harriet de Wit 7 Developmental Considerations in Gene Identification Efforts .................................................... 141 Danielle M. Dick 8 Enhancing Addiction Genetics via Behavioral Economic Intermediate Phenotypes .................................... 157 James MacKillop and John Acker 9 Using Functional Magnetic Resonance Imaging to Develop Intermediate Phenotypes for Substance Use Disorders ........ 189 Rachel E. Thayer and Kent E. Hutchison 10 Implicit Cognition: An Intermediate Phenotype for Addiction? ................................................. 207 Reinout W. Wiers, Eske M. Derks, and Thomas E. Gladwin 11 The Role of Genetics in Addiction and the Expectancy Principle .................................................. 237 Mark S. Goldman and Richard R. Reich 12 Intermediate Phenotypes for Alcohol Use and Alcohol Dependence: Empirical Findings and Conceptual Issues ....... 257 Michael Windle 13 Epigenetic Effects and Intermediate Phenotypes ............. 275 Steven R.H. Beach, Meg Gerrard, Gene H. Brody, Ronald L. Simons, Steven M. Kogan, Frederick X. Gibbons, and Robert A. Philibert 14 Differential Sensitivity to Context: GABRG1 Enhances the Acquisition of Prototypes That Serve as Intermediate Phenotypes for Substance Use ............................... 303 Ronald L. Simons, Man Kit Lei, Steven R.H. Beach, Gene H. Brody Robert A. Philibert, Frederick X. Gibbons, and Meg Gerrard 15 From Genes to Behavior Change: Treatment Response as an Intermediate Phenotype ..................................... 327 Courtney J. Stevens, Hollis C. Karoly, Renee E. Magnan, and Angela D. Bryan 16 Using Intermediate Phenotypes to Bridge the Gap between Human and Mouse Genetics ................................... 345 Clarissa C. Parker and Abraham A. Palmer Index ......................................................... 373