Introduction: Developmental Biology, Regenerative Medicine
and Stem Cells: The Hope Machine is Justified .................. ix
David Warburton
Foreword: Towards Broader Approaches to Stem Cell Signaling
and Therapeutics .................................. xiii
Edwin Jesudason
Chapter 1 Pluripotent Stem Cells from the Early Embryo ......... 1
Claire E. Cuddy and Martin F. Pera
Chapter 2 The First Cell Fate Decision During Mammalian
Development ......................................... 25
Melanie D. White and Nicolas Plachta
Chapter 3 Asymmetric Cell Divisions of Stem/Progenitor Cells .. 41
Ahmed HK 'El-Hashash
Chapter 4 Microenvironmental Modulation of Stem Cell
Differentiation with Focus on the Lung .............. 59
Shimon Lecht, Collin T. Stabler, Seda Karamil,
Athanasius Mantalaris, Ali Samadikuchaksaraei,
Julia M. Polak and Peter I. Lelkes
Chapter 5 Smart Matrices for Distal Lung Tissue Engineering ... 99
Mark J. Mondrinos and Peter I. Lelkes
Chapter 6 Skin Stem Cells and Their Roles in Skin
Regeneration and Disorders ......................... 125
Chao-Kai Hsu, Chao-Chun Yang and Shyh-Jou Shieh
Chapter 7 Stem Cell Recruitment and Impact in Skin Repair
and Regeneration ................................... 145
Tim Hsu, Tai-Lan Tuan and Yun-Shain Lee
Chapter 8 Epigenetic and Environmental Regulation of Skin
Appendage Regeneration ............................. 163
Ting-Xin Jiang, Chih-Chiang Chen, Michael
W. Hughes, Cheng-Ming Chuong and Randall Widelitz
Chapter 9 Cranial Neural Crest: An Extraordinarily
Migratory and Multipotent Embryonic Cell
Population ......................................... 185
Samuel G. Cox and J. Gage Crump
Chapter 10 Modeling Neurodegenerative Diseases and
Neurodevelopmental Disorders with Reprogrammed
Cells .............................................. 215
Kate E. Galloway and Justin K. Ichida
Chapter 11 Cytokine Regulation of Intestinal Stem Cells ....... 261
Philip E. Dubé, Unice J.K. Soh and D. Brent Polk
Chapter 12 The Intestinal Stem Cell Niche and Its
Regulation by ErbB Growth Factor Receptors ......... 273
Dana Almohazey and Mark R. Frey
Chapter 13 Tissue Engineering: Intestine ...................... 295
Avafia Y. Dossa, Kathy A. Schall, Tracy C.
Grikscheit and Christopher P. Gayer
Chapter 14 Liver Stem and Progenitor Cells in Development,
Disease and Regenerative Medicine .................. 313
Nirmala Mavila and Kasper S. Wang
Chapter 15 Lung Mesenchymal Stem Cells ........................ 331
Wei Shi
Chapter 16 FGF Signaling in Lung Stem and Progenitor Cells .... 337
Soula Danopoulos and Denise AI Alam
Chapter 17 Bioengineering Distal Airways ...................... 353
Christine Finck and Todd Jensen
Chapter 18 The Isolation and Molecular Characterization of
Cancer Stem Cells (Aggressive Endophenotypes) in
Individual Lung Cancers ............................ 373
Raj K. Batra, Scott Oh and Saroj Basak
Chapter 19 Mesenchymal Stromal Cell-Based Therapies
for Lung Diseases and Critical Illnesses ........... 399
Fernanda Cruz, Patricia RM Rocco and Daniel
J. Weiss
Chapter 20 Heart Regeneration and Repair: What We Have
Learned From Model Organisms ....................... 435
Laurent Gamba, Michael R. Harrison and Ching-Ling
Lien
Chapter 21 Leveraging Structure-Based Rational Drug Design
and Nanotechnology to Destroy Leukemic, Stem
Cells .............................................. 449
Fatih M. Uckun, Jianjun Cheng, Cheney Mao and
Sanjive Qazi
Chapter 22 Placenta-Derived Stem Cells: Development and
Preclinical Applications for Regenerative
Medicine ........................................... 465
Jennifer Izumi Divine, Нее Kyung Jung and Toshio
Miki
Chapter 23 Stem Cells in the Real World: Environmental
Impacts ............................................ 485
Theresa M. Bastain, Lu Gao and Frank D. Gilliland
Chapter 24 Establishing a Research Grade Human Pluripotent
Stem Cell Laboratory ............................... 497
Laura-Marie Nucho and Victoria Fox
Index ......................................................... 515
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