Preface ....................................................... vii
Color Plates ................................................. xiii
Part I Innate and Adaptive Immunity ............................ 1
1 Immunology ................................................... 3
Cindy Takeuchi and Paul Wentworth
2 Superantigens ............................................... 27
Matthew D. Baker and K. Ravi Acharya
3 Antigen Presenting Cells (APCs) ............................. 43
Harald Kropshofer and Anne B. Vogt
4 Cell Mediated Immune Defence ................................ 93
Martin F. Bachmann and Thomas M. Kundig
5 Immunologic Memory ......................................... 113
Alexander Ploss and Eric G. Pamer
Part II Signaling in the Immune System ....................... 135
6 Molecular Mediators: Cytokines ............................. 137
Jean-Marc Cavaillon
7 Interleukins ............................................... 167
Anthony Meager
8 Viral Inhibitors and Immune Response Mediators: The
Interferons ................................................ 205
Anthony Meager
9 Signaling Through JAKs and STATs: Interferons Lead the
Way ........................................................ 241
Christian Schindler
Part III Techniques .......................................... 269
10 Flow Cytometry ............................................. 271
Michael G. Ormerod
11 Immunoassays ............................................... 295
James P. Gosling
12 Genetic Engineering of Antibody Molecules .................. 319
Manuel L. Penichet and Sherie L. Morrison
Part IV Immunological Disorders .............................. 343
13 Autoantibodies and Autoimmunity ............................ 345
Kenneth Michael Pollard
14 Synovial Mast Cells in Inflammatory Arthritis .............. 367
Theoharis C. Theoharides
15 Molecular and Cell Biology of AIDS/HIV ..................... 395
Andrew M.I. Lever
Index ...................................................... 421
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