Characterization of biomaterials / ed. by A.Bandyopadhyay, S.Bose. - Waltham; Oxford, 2013. - xii, 437 p.: ill. - (Material science and engineering). - 419-437. - Пер. загл.: Характеристика биоматериалов. - ISBN 978-1-12-415800-9  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Preface ........................................................ ix List of Contributors ........................................... xi 1 Introduction to Biomaterials Susmita Bose and Amit Bandyopadhyay 1.1 Introduction ............................................ 1 1.2 Types of Materials ...................................... 2 1.3 Biomaterials and Biocompatibility ....................... 4 1.4 Types of Biomaterials ................................... 5 1.5 Properties of Biomaterials .............................. 6 1.6 Biomaterials Characterization and Outline of this Book .. 8 1.7 Summary ................................................. 9 Suggested Further Reading ............................... 9 2 Physical and Chemical Characterization of Biomaterials T.S. Sampath Kumar 2.1 Microstructural Characterization ....................... 11 2.2 Scanning Probe Microscopy .............................. 20 2.3 X-ray Diffraction and Scattering Methods ............... 28 2.4 FT-IR Spectroscopy ..................................... 32 2.5 DLS Techniques ......................................... 35 2.6 Contact Angle Measurements ............................. 38 2.7 Mercury Intrusion Porosimetry .......................... 41 2.8 Gas Adsorption Measurements ............................ 44 2.9 Summary ................................................ 46 References ............................................. 47 3 Mechanical Characterization of Biomaterials Ryan K. Roeder 3.1 Introduction ........................................... 50 3.2 Fundamental Concepts ................................... 51 3.3 Specimens .............................................. 62 3.4 Application and Measurement of Load and Deformation .... 64 3.5 Environment ............................................ 91 3.6 Data Acquisition and Analysis .......................... 95 Acknowledgments ........................................ 96 References ............................................. 97 4 Surface Characterization of Biomaterials Huaiyu Wang and Paul K. Chu 4.1 X-ray Photoelectron Spectroscopy ...................... 106 4.2 Auger Electron Spectroscopy ........................... 111 4.3 Secondary Ion Mass Spectrometry (SIMS) ................ 113 4.4 Surface Matrix-Assisted Laser Desorption Ionization Mass Spectrometry .......................... 122 4.5 Infrared IR Spectroscopy .............................. 125 4.6 Raman Spectroscopy .................................... 127 4.7 Electron Energy Loss Spectroscopy ..................... 131 4.8 Ultraviolet-Visible Spectroscopy ...................... 132 4.9 Light Microscopy and Confocal Microscopy .............. 134 4.10 Scanning Electron Microscopy .......................... 135 4.11 Scanning Tunnelling Microscopy and Atomic Force Microscopy ............................................ 144 4.12 Profilometry .......................................... 151 4.13 Contact Angle Measurement ............................. 152 4.14 Ellipsometry .......................................... 157 4.15 Conclusions ........................................... 161 References ............................................ 161 5 5.1 In Vitro Characterization of Cell—Biomaterials Interactions Y.M. Thasneem and Chandra P. Sharma 5.1.1 Introduction ................................... 176 5.1.2 Basics of Cell Biology ......................... 177 5.1.3 Materials for Biomedical Applications (Biomaterials) ................................. 179 5.1.4 Cell—Nanotopography Responses on Synthetic Substrates ..................................... 188 5.1.5 Techniques to Evaluate Cell—Material Interactions ................................... 192 Acknowledgments ....................................... 200 References ............................................ 201 5.2 Characterization of Bacteria - Biomaterial Interactions, from a Single Cell to Biofilms Nehal I. Abu-Lail and Haluk Beyenal 5.2.1 Introduction ................................... 208 5.2.2 Quantification of Bacterial Interactions with Surfaces .................................. 213 5.2.3 Atomic Force Microscopy (AFM) Use in Investigations of Biological Systems ........ 215 5.2.4 Use of AFM for Quantification of Bacteria - Biomaterial Interactions ....................... 221 5.2.5 Examples from the Literature of AFM Studies of Bacteria - Biomaterial Interactions ......... 223 5.2.6 Characterization of Biofilms on Biomaterial Surfaces ....................................... 235 5.2.7 Quantifying Biofilm Structure .................. 237 5.2.8 Analysis of Biofilm Images ..................... 241 5.2.9 Conclusions .................................... 242 Sources for Further Information and Advice ............ 242 Acknowledgments ....................................... 242 References ............................................ 242 6 In Vivo Characterization of Biomaterials Samit K. Nandi and Subhasish Biswas 6.1 Introduction .......................................... 256 6.2 Ideal Characteristics of Biomaterial for in vivo Application ........................................... 258 6.3 Animal Model in Orthopaedic Surgery ................... 259 6.4 Animal Models in Spinal Surgery and Characterization of Biomaterials ....................................... 261 6.5 Characterization Parameters ........................... 263 6.6 Biodistribution Studies ............................... 284 6.7 In Vivo Characterization of Biomaterials in Soft Tissue Surgery ........................................ 286 6.8 Summary ............................................... 290 References ............................................ 290 7 7.1 Structural and Biological Characterization of Scaffolds Julia Will, Rainer Detsch and Aldo R. Boccaccini 7.1.1 Introduction ................................... 299 7.1.2 Characterization of Scaffolds Morphology and Porosity ................................... 301 7.1.3 Permeability ................................... 302 7.1.4 Mechanical Characterization of Scaffolds ....... 302 7.1.5 Biological Characterization of Scaffolds ....... 303 7.1.6 Summary ........................................ 306 References ............................................ 306 7.2 Mechanical Properties of Bioceramic Coatings on Medical Implants Mangal Roy, Amit Bandyopadhyay and Susmita Bose 7.2.1 Introduction ................................... 311 7.2.2 Coating Microstructure ......................... 312 7.2.3 Wear Properties ................................ 313 7.2.1 Bond Strength of Coatings ...................... 315 7.2.5 Fatigue Properties of Coatings ................. 317 7.2.6 Shear Testing of Coatings ...................... 318 7.2.7 Summary ........................................ 319 References ............................................ 319 8 Characterization of Orthopaedic Devices Imran Khan, Malcolm Naylor and Gautam Gupta 8.1 Mechanical Testing of Orthopaedic Devices ............. 323 8.2 Tribological Testing of Joint Implants ................ 336 8.3 Metallic Coatings for Orthopaedic Devices ............. 345 References ............................................ 351 9 Characterization of Cardiovascular Implantable Devices Ming H. Wu and Hengchu Cao 9.1 Cardiovascular System ................................. 355 9.2 Types of Cardiovascular Implantable Devices ........... 359 9.3 In Vitro Characterization of Cardiovascular Implantable Devices ................................... 377 References ............................................ 414 Index ......................................................... 419