Preface ......................................................... v
Chapter 1
Cellular and Molecular Mechanisms of Plaque Rupture ............. 1
Prediman K. Shah
Chapter 2
Apoptosis and Plaque Vulnerability ............................. 19
Martin R. Bennett
Chapter 3
Animal Models of Vulnerable Plaque ............................. 35
Harry C. Lowe, Levon M. Khachigian, Leonard Kritharides, and
Jason L. Johnson
Chapter 4
Diagnosis of Vulnerable Plaques in the Cardiac
Catheterization Laboratory ..................................... 53
Johannes A. Schaar, Evelyn Regar, Chourmouzios A. Arampatzis,
Arjen R.A. van der Wen, Cornells J. Slager, Frank J. Gljsen,
Jolanda J. Wentzel, Pint J. de Feyter, A.F.W. van der Steen,
and Patrick W. Serruys
Chapter 5
Imaging of High-Risk Atherosclerotic Plaque by Intravascular
Ultrasound: Focal Assessment of Morphology and Vulnerability
or Systemic Assessment of Disease Burden and Activity? ......... 67
Paul Schoenhagen, Richard D. White, and Steven E. Nissen
Chapter 6
Optical Coherence Tomography for Detection of Vulnerable
Plaque ......................................................... 85
Fabian Moselewski, Stephan Achenbach, and Ik-Kyung Jang
Chapter 7
Magnetic Resonance Imaging of High-Risk Plaque ................ 101
Stephen G. Worthley and Juan J. Badimon
Chapter 8
Nuclear Imaging of the Vulnerable Plaque: Single Photon
Emission Computed Tomography (SPECT) and Positron Emission
Tomography (PET) .............................................. 129
John Davies, James Rudd, Tim Fryer, Jonathan Gillard, and
Peter Weissberg
Chapter 9
Identification of Vulnerable Plaques: The Role of
Thermography .................................................. 145
Konstantinos Toutouzas, Sophia Vaina, and Christodoulos
Stefanadis
Chapter 10
Treatment of Vulnerable Plaques: Current and Future
Strategies .................................................... 161
Leonard Kritharides, David Brieger, S. Benedict Freedman,
and Harry C. Lowe
Index ......................................................... 203
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