Part I Introduction
1 Introduction to Immunotoxicity ............................... 3
Keith D. Salazar and Rosana Schafer
2 The Environment-Immune Route to Chronic Disease ............. 31
Rodney R. Dietert and Robert W. Luebke
Part II Allergic Diseases
3 Asthma and Respiratory Allergic Disease ..................... 51
David M. Lehmann and Marc A. Williams
4 Cutaneous Allergies ........................................ 103
David A. Basketter and John P. McFadden
5 Food Allergies ............................................. 127
Christal C. Bowman
Part III Autoimmune and Inflammatory Diseases and Conditions
6 Factors Involved in Onset of Type 1 Diabetes ............... 153
Anne Cooke and Paola Zaccone
7 Rheumatoid Arthritis ....................................... 171
Jean C. Pfau
8 Environment, Immune Dysfunction, and Systemic Lupus
Erythematosus .............................................. 193
Moran Landau Rabbi, Ilan Ben-Zvi, Nancy Agmon-Levin, and
Yehuda Shoenfeld
9 Multiple Sclerosis, Alzheimer's Disease, and
Inflammation: A Hypothetical View .......................... 215
Margaret S. Bynoe and Christophe Viret
10 Immune Dysfunction in Autism Spectrum Disorders ............ 253
Milo Careaga, Judy Van de Water, and Paul Ashwood
11 Atherosclerosis and Inflammatory Heart Disease ............. 271
DeLisa Fairweather
12 Inflammatory Bowel Disease and Celiac Disease:
Environmental Risks Factors and Consequences ............... 291
Rodney R. Dietert
13 COPD and Other Inflammatory Diseases of the Lung: Focus
on AhR Signaling ........................................... 313
Celine A. Beamer, Benjamin P. Seaver, and David M.
Shepherd
14 Environment, the Immune System, and Depression: An
Integrative Review and Discussion of the Infection-
Defense Hypothesis ......................................... 345
Midori Tanaka, Sherry Anders, and Dennis K. Kinney
Part IV Infections and Cancer
15 Environmental Toxicants and Susceptibility to Infection .... 389
Carsten Heilmann
16 Childhood Acute Leukemia ................................... 399
Joseph Wiemels
Part V Prevention of Chronic Diseases
17 Reducing the Prevalence of Immune-Based Chronic Disease .... 419
Rodney R. Dietert, Jamie C. DeWitt, and Robert W. Luebke
About the Authors ............................................. 441
Index ......................................................... 443
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