Preface ........................................................ ix
1 The Role of Antioxidants in Human Health ..................... 1
Saikat Sen and Raja Chakraborty
2 Pathophysiological Implications of Altered Redox Balance
in HIV/AIDS Infection: Diagnosis and Counteract
Interventions ............................................... 39
L. Gil del Valle, Ph.D.
3 Thermodynamics of Free Radical Reactions and the Redox
Environment of a Cell ....................................... 71
Klaudia Jomova and Marian Valko
4 Oxidative Stress in the Metabolism of Estrogens Leading to
Cancer Initiation: Prevention by Specific Antioxidants ...... 83
Eleanor G. Rogan and Ercole L. Cavalieri
5 Polyphenol Compounds as Antioxidants for Disease
Prevention: Reactive Oxygen Species Scavenging, Enzyme
Regulation, and Metal Chelation Mechanisms in E. coli and
Human Cells ................................................. 99
Hsiao C. Wang and Julia L. Brumaghim
6 DNA-Protective Mechanisms of Glutathione Intervention in
Catechol-Mediated Oxidative DNA Damage in the Presence of
Copper(II) Ions ............................................ 177
Maria Hepel, Magdalena Stobiecka, Janet Peachey, and
Jeremiah Miller
7 Antioxidant Effectiveness in Preventing Paraquat-Mediated
Oxidative DNA Damage in the Presence of H2O2 ............... 211
Magdalena Stobiecka, Amanda Prance, Kaitlin Coopersmith,
and Maria Hepel
8 Artificial Nanoparticle Antioxidants ....................... 235
Erica Sharpe, Daniel Andreescu, and Silvana Andreescu
9 Cerium Oxide Nanoparticles for the Treatment of
Neurological Oxidative Stress Diseases ..................... 255
A.Y. Estevez and J.S. Erlichman
10 Detection of Superoxide and Hydrogen Peroxide from Living
Cells Using Electrochemical Sensors ........................ 289
Szilveszter Gáspár
11 Peroxynitrite and Nitroxidative Stress: Detection Probes
and Micro-Sensors. A Case of a Nanostructured Catalytic
Film ....................................................... 311
Serban F. Peteu, Saleem Banihani, Mutha M. Gunesekera,
Pubudu Peiris, Oana A. Sicuia, and Mekki Bayachou
12 Blue Native PAGE and Mass Spectrometry as an Approach for
the Investigation of Stable and Transient Protein-Protein
Interactions ............................................... 341
Alisa G. Woods, Izabela Sokolowska, Rama Yakubu, Melissa
Butkiewicz, Martin LaFleur, Christopher Talbot, and
Costel C. Darie
13 Mass Spectrometry for Proteomics-Based Investigation of
Oxidative Stress and Heat Shock Proteins .................. 369
Izabela Sokolowska, Alisa G. Woods, Jessica Wagner,
Jeannette Dorler, Kelly Wormwood, Johannes Thome, and
Costel C. Darie
Editors' Biographies .......................................... 413
Indexes
Author Index .................................................. 417
Subject Index ................................................. 419
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