CONTRIBUTORS .................................................. vii
PREFACE ........................................................ xi
PART I INTRODUCTION CHAPTERS .................................... 1
1 BIOTECHNOLOGY TOOLS FOR GREEN SYNTHESIS: ENZYMES, METABOLIC
PATHWAYS, AND THEIR IMPROVEMENT BY ENGINEERING ............... 3
2 HOW GREEN CAN THE INDUSTRY BECOME WITH BIOTECHNOLOGY? ....... 23
3 EMERGING ENZYMES AND THEIR SYNTHETIC APPLICATIONS ........... 45
4 REACTION EFFICIENCIES AND GREEN CHEMISTRY METRICS OF
BIOTRANSFORMATIONS .......................................... 67
PART II APPLICATION AND CASE STUDIES-PHARMACEUTICALS AND FINE
CHEMICALS ...................................................... 89
5 BIOCATALYTIC ROUTES TO CHIRAL INTERMEDIATES FOR
DEVELOPMENT OF DRUGS ........................................ 91
6 TRANSGLUTAMINASE FOR PROTEIN DRUG MODIFICATION: PEGYLATION
AND BEYOND ................................................. 151
7 MICROBIAL PRODUCTION OF PLANT-DERIVED PHARMACEUTICAL
NATURAL PRODUCTS THROUGH METABOLIC ENGINEERING:
ARTEMISININ AND BEYOND ..................................... 173
8 TOWARD GREENER THERAPEUTIC PROTEINS ........................ 197
PART III APPLICATION AND CASE STUDIES-FLAVOR & FRAGRANCE,
AGROCHEMICALS AND FINE CHEMICALS .............................. 221
9 OPPORTUNITIES FOR BIOCATALYSIS IN THE FLAVOR, FRAGRANCE,
AND COSMETIC INDUSTRY ...................................... 223
10 APPLICATION OF BIOCATALYSIS IN THE AGROCHEMICAL INDUSTRY ... 255
11 GREEN PRODUCTION OF FINE CHEMICALS BY ISOLATED ENZYMES ..... 277
12 WHOLE CELL PRODUCTION OF FINE CHEMICALS AND INTERMEDIATES .. 299
PART IV APPLICATION AND CASE STUDIES-POLYMERS AND RENEWABLE
CHEMICALS ..................................................... 327
13 GREEN CHEMISTRY FOR THE PRODUCTION OF BIODEGRADABLE,
BIORENEWABLE, BIOCOMPATIBLE, AND POLYMERS .................. 329
14 ENZYMATIC DEGRADATION OF LIGNOCELLULOSIC BIOMASS ........... 361
15 BIOCONVERSION OF RENEWABLES-PLANT OILS ..................... 391
16 MICROBIAL BIOPROCESSES FOR INDUSTRIAL-SCALE CHEMICAL
PRODUCTION ................................................. 429
INDEX ......................................................... 469
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