Preface ......................................................... v
Contributors ................................................... ix
Part I Functionalization
1 Non-covalent Attachment of Proteins to Single-Walled
Carbon Nanotubes ............................................ 3
Luis F.F. Neves, Ta-Wei Tsai, Naveen R. Palwai, David
E. Martyn, Yongqiang Tan, David W. Schmidtke, Daniel
E. Resasco, and Roger G. Harrison
2 Covalent Conjugation of Multi-walled Carbon Nanotubes with
Proteins ..................................................... 9
Changqing Yi, Suijian Qi, Dawei Zhang, and Mengsu Yang
3 Covalently Linked Deoxyribonucleic Acid with Multi-walled
Carbon Nanotubes: Synthesis and Characterization ............ 19
Weiwei Chen, Changqing Yi, Tzang Chi-Hung, Shuit-Tong Lee,
and Mengsu Yang
4 Temperature and pH-Responsive "Smart" Carbon Nanotube
Dispersions ................................................. 27
Dan Wang and Liwei Chen
Part II Toxicity
5 Effects of Carbon Nanotubes on the Proliferation and
Differentiation of Primary Osteoblasts ...................... 41
Dawei Zhang, Changqing Yi, Suijian Qi, Xinsheng Yao, and
Mengsu Yang
6 Carbon Nanotube Uptake and Toxicity in the Brain ............ 55
Leying Zhang, Darya Alizadeh, and Behnam Badie
7 In Vitro and In Vivo Biocompatibility Testing of
Functionalized Carbon Nanotubes ............................. 67
Gianni Ciofani, Vittoria Raffa, Orazio Vittorio, Alfred
Cuschieri, Tommaso Pizzorusso, Mario Costa, and Giuseppe
Bardi
8 Real-Time Monitoring of Cellular Responses to Carbon
Nanotubes ................................................... 85
Qingxin Mu, Shumei Zhai, and Bing Yan
9 Reducing Nanotube Cytotoxicity Using a Nano-
Combinatorial Library Approach .............................. 95
Qiu Zhang, Hongyu Zhou, and Bing Yan
10 DNA Damage by Carbon Nanotubes Using the Single Cell Gel
Electrophoresis Technique .................................. 109
Olga Zeni and Maria Rosaria Scarfi
Part III Trafficking
11 Assessment of Cellular Uptake and Cytotoxicity of Carbon
Nanotubes Using Flow Cytometry ............................. 123
Khuloud T. Al-Jamal and Kostas Kostarelos
12 Cell Trafficking of Carbon Nanotubes Based on
Fluorescence Detection ..................................... 135
Monica H. Lamm and Pu Chun Ke
13 Carbon Nanotubes as Intracellular Carriers for Multidrug
Resistant Cells Studied by Capillary Electrophoresis-
Laser Tnduced Fluorescence ................................. 153
Ruibin Li, Hanfa Zou, Нua Xiao, and Renan Wu
Part IV Scaffolds
14 Carbon Nanotube-Based Neurochips ........................... 171
Moshe David-Pur, Mark Shein, and Yael Hanein
15 Effect of Carbon Nanotubes on HepG2 Adhesion and
Spreading .................................................. 179
Suijian Qi, Changqing Yi, Dawei Zhang, and Mengsu Yang
Part V Biosensors
16 Enzymatic Detection Based on Carbon Nanotubes .............. 197
Martin Pumera
17 Carbon Nanotube Biosensors Based on Electrochemical
Detection .................................................. 205
Martin Pumera
18 Biosensors Based on Carbon Nanotube-Network Field-Effect
Transistors ................................................ 213
Cristina C. Cid, Jordi Riu, Alicia Maroto, and F. Xavier
Rius
19 Detection of Biomarkers with Carbon Nanotube-Based
Immunosensors .............................................. 227
Samuel Sánchez, Esteve Fàbregas, and Martin Pumera
20 Carbon Nanotube Biosensors with Aptamers as Molecular
Recognition Elements ....................................... 239
Hye-Mi So, Dong-Won Park, Hyunju Chang, and Jeong-O Lee
Index ......................................................... 251
|