Nanotoxicity: methods and protocols / ed.by J.Reineke. - New York: Humana Press, 2012. - xii, 414 p.: ill. - (Methods in molecular biology; 926). - Bibliogr. at the end of the chapters. - ISBN 978-1-62703-001-4; ISSN 1064-3745  Место хранения:   040 | Институт биофизики СО РАН | Красноярск | Библиотека

Оглавление / Contents

Preface ......................................................... v Contributors ................................................... ix 1 Historical Overview of Nanotechnology and Nanotoxicology ..... 1 Annette Santamaria 2 Characterization of Nanomaterials for Toxicological Studies ..................................................... 13 Kevin W. Powers, Paul L. Carpinone, and Kerry N. Siebein 3 Methods for Understanding the Interaction Between Nanoparticles and Cells ..................................... 33 Pilar Rivera Gil, Martin J.D. Clift, Barbara Rothen Rutishauser, and Wolfgang J. Parak 4 Single-Cell Gel Electrophoresis (Comet) Assay in Nano- genotoxicology .............................................. 57 Maricica Pacurari and Vincent Castranova 5 Single-Cell Nanotoxicity Assays of Superparamagnetic Iron Oxide Nanoparticles ......................................... 69 Trisha Eustaquio and James F. Leary 6 Western Blot Analysis ....................................... 87 Seishiro Hirano 7 Application of Reverse Transcription-PCR and Real-Time PCR in Nanotoxicity Research ................................ 99 Yiqun Mo, Rong Wan, and Qunrvei Zhang 8 Deriving TC50 Values of Nanoparticles from Electrochemical Monitoring of Lactate Dehydrogenase Activity Indirectly .... 113 Fuping Zhang, Na Wang, Fang Chang, and Shuping Bi 9 Enzyme-Linked Immunosorbent Assay of IL-8 Production in Response to Silver Nanoparticles ........................ 131 Eun-Jeong Yang, Jiyoung Jang, Dae-Hyoun Lim, and In-Hong Choi 10 Metabolomics Techniques in Nanotoxicology Studies .......... 141 Laura K. Schnackenberg, Jinchun Sun, and Richard D. Beger 11 Nanoparticle Uptake Measured by Flow Cytometry ............. 157 Yuko Ibuki and Tatsushi Toyooka 12 Determining Biological Activity of Nanoparticles as Measured by Flow Cytometry ................................. 167 Jennifer F. Nyland 13 Whole Cell Impedance Biosensoring Devices .................. 177 Evangelia Hondroulis and Chen-Zhong Li 14 Free Energy Calculation of Permeant-Membrane Interactions Using Molecular Dynamics Simulations ....................... 189 Paolo Elvati and Angela Violi 15 Screening of Fullerene Toxicity by Hemolysis Assay ......... 203 Federica Tramer, Tatiana Da Ros, and Sabina Passamonti 16 Assessment of In Vitro Skin Irritation Potential of Nanoparticles: RHE Model ................................ 219 P. Balakrishna Murthy, A. Sairam Kishore, and P. Surekha 17 In Vivo Methods of Nanotoxicology .......................... 235 Khaled Greish, Giridhar Thiagarajan, and Hamidreza Ghandehari 18 The Luminescent Bacteria Test to Determine the Acute Toxicity of Nanoparticle Suspensions ....................... 255 Ana Garcia, Sonia Recillas, Antoni Sánchez, and Xavier Font 19 The Primacy of Physicochemical Characterization of Nanomaterials for Reliable Toxicity Assessment: A Review of the Zebrafish Nanotoxicology Model ...................... 261 John P. Bohnsack, Shoeleh Assemi, Jan D. Miller, and Darin Y. Furgeson 20 Application of Embryonic and Adult Zebrafish for Nanotoxicity Assessment .................................... 317 Jiangxin Wang, Xiaoshan Zhu, Yongsheng Chen, and Yung Chang 21 Applications of Subsurface Microscopy ...................... 331 Laurene Tetard, Ali Passian, Rubye H. Farahi, Brynn H. Voy, and Thomas Thundat 22 Application of ICP-MS for the Study of Disposition and Toxicity of Metal-Based Nanomaterials ...................... 345 Mo-Hsiung Yang, Chia-Hua Lin, Louis W. Chang, and Pinpin Lin 23 Quantitative Nanoparticle Organ Disposition by Gel Permeation Chromatography .................................. 361 Abdul Khader Mohammad and Joshua Reineke 24 Physiologically Based Pharmacokinetic Modeling for Nanoparticle Toxicity Study ................................ 369 Mingguang Li and Joshua Reineke 25 Biophysical Methods for Assessing Plant Responses to Nanoparticle Exposure ...................................... 383 Tatsiana A. Ratnikova, Ran Chen, Priyanka Bhattacharya, and Pu Chun Ke 26 In Vivo Nanotoxicity Assays in Plant Models ................ 399 Mamta Kumari, Vinita Ernest, Amitava Mukherjee, and Natarajan Chandrasekaran Index ......................................................... 411