Part I Fundamentals of Nanotechnology in Drug Delivery
1 Physicochemical Principles of Nanosized Drug Delivery
Systems ...................................................... 3
Daniel P. Otto and Melgardt M. de Villiers
2 Block Copolymer Synthesis for Nanoscale Drug and Gene
Delivery .................................................... 35
Motoi Oishi and Yukio Nagasaki
3 Supercritical Fluid Technology for Nanotechnology in Drug
Delivery .................................................... 69
Mohammed J. Meziani, Pankaj Pathak, and Ya-Ping Sun
4 Nanotubes, Nanorods, Nanofibers, and Fullerenes for
Nanoscale Drug Delivery .................................... 105
Jessica B. Melanko, Megan E. Pearce, and Aliasger
K. Salem
5 Drug Loading into and In Vitro Release from Nanosized
Drug Delivery Systems ...................................... 129
Anja Judefeind and Melgardt M. de Villiers
6 Nanotechnology-Based Biosensors in Drug Delivery ........... 163
Guigen Zhang
Part II Biopharmaceutical, Physiological, and Clinical
Considerations for Nanotechnology in Drug Delivery
7 Nanomaterials and Biocompatibility: BioMEMS and
Dcndrimers ................................................. 193
Sean T. Zuekerman and Weiyuan John Kao
8 Nanomaterials and Biocompatibility: Carbon Nanotubes and
Fullerenes ................................................. 229
Sean T. Zuckerman and Weiyuan John Kao
9 Factors Controlling Pharmacokinetics of Intravenously
Injected Nanoparticulate Systems ........................... 267
S. Моеin Moghimi and Islam Hamad
10 Controlled Release and Nanotechnology ...................... 283
Tania Betancourt, Amber Doiron, Kimherly A. Homan, and
Lisa Brannon-Peppas
11 Nanotechnology for Intracellular Delivery and Targeting .... 313
Vladimir P. Torchilin
Part III Nanotechnology for the Delivery of Small Molecules,
Proteins and Nucleic Acids
12 Nano-sized Advanced Delivery Systems as Parenteral
Formulation Strategies for Hydrophobic Anti-cancer Drugs ... 349
Patrick Lim Soo, Michael Dunne, Jubo Liu, and Christine
Allen
13 Engineering of Amphophilic Block Copolymers for Drug and
Gene Delivery .............................................. 385
Xiao-Bing Xiong, Hasan Uludağ, and Afsaneh Lavasanifar
14 РАМАМ Dendrimers as Nanoscale Oral Drug Delivery Systems ... 421
Kelly M. Kitchens and Hamidreza Ghandehari
15 Nanoemulsions for Intravenous Drug Delivery ................ 461
Jonathan P. Fast and Sandra Mecozzi
16 Nanotechnology for Cancer Chemotherapy ..................... 491
Alisar S. Zahr and Michael V. Pishko
17 Nanotechnology for Cancer Vaccine Delivery ................. 519
Samar Hamdy, Aws Alshamsan, and John Samuel
18 Stimuli-Sensitive Nanotechnology for Drug Delivery ......... 545
Andre G. Skirtach and Oliver Kreft
Part IV A Look to the Future of Nanotechnology in Drug
Delivery
19 Nanotechnology in Drug Delivery: Past, Present, and
Future ..................................................... 581
Sungwon Kim, II Keun Kwon, Ick Chan Kwon, and Kinam Park
20 Nanotechnology in Drug Development and Life Cycle
Management ................................................. 597
Shingai Majuru and Moses O. Oyewumi
21 Nanopharmaceuticals: Challenges and Regulatory
Perspective ................................................ 621
Rakhi B. Shah and Mansoor A. Khan
Index ...................................................... 647
|