Preface ......................................................... v
I. General and Cellular Aspects
1 Apoptotic Pathways in Mitochondria ........................... 3
Ozgur Kutuk and Huveyda Basaga
2 Human Genetic Defects in Apoptosis Pathways and Processes ... 19
Jeremiah C. Davis and Helen C. Su
3 Polyphenols and Apoptosis ................................... 37
Claudio Giovannini, Beatrice Scazzocchio, Rosaria Vari and
Roberta Masella
4 How Caspase Proteases Regulate Cell Fate .................... 55
Carol Evans and Lynn Megeney
5 Role of Calpain in Apoptotic Process Involved in
Neurodegenerative Diseases .................................. 73
Natalia Crespo-Biel, Anna M. Canudas, Antoni Camins and
Mercè Pallàs
6 TNF-related Apoptosis-inducing Ligand (TRAIL) ............... 87
Simone Fulda
7 The Role of Endoplasmic Reticulum (ER) Stress in Mediating
the Apoptotic Effect of Selenium Compounds .................. 99
Hidemi Rikiishi and Maiko Suzuki
8 Nuclear Steroid Receptors in Apoptosis ..................... 115
Joana D. Amaral, Susana Solá, Clifford J. Steer and
Cecília M.P. Rodrigues
9 Mitochondrial Morphological Dynamics in Apoptosis .......... 133
Craig Brooks and Zheng Dong
10 Apoptotic Cell Uptake and Degradation ...................... 149
Leanne E. Lewis, Judith M. Bain and Lars-Peter Erwig
II. Metabolic and Organ Specific Diseases
11 Apoptosis in Skeletal Muscle Health and Conditions
of Muscle Wasting .......................................... 167
Stephen E. Alway
12 Apoptosis in the Spinal Column — Its Understanding will
Help Develop Strategies for the Treatment of Chronic Back
Pain ....................................................... 183
Ashish D. Diwan
13 Apoptosis in the Liver ..................................... 199
Ying-Hong Shi, Jia Fan, Zhen-Bin Ding and Xiao-Ming Yin
14 Apoptosis in Alcoholic Liver Disease ....................... 215
D. Gyamfi, H.E. Everitt and V.B. Patel
15 Pancreatic Beta-Cell Apoptosis ............................. 229
Dan S. Luciani and James D. Johnson
16 Oxidative Stress and Apoptosis ............................. 245
J.M. Matés, J.A. Segura, F.J. Alonso and J. Márquez
III. Cancer
17 Apoptosis in Lung Cancer ................................... 263
Shou Wei Han and Jesse Roman
18 Inhibition of Apoptosis in Leukemia: BCR-ABL Induced
Leukemogenesis ............................................. 277
Rajan Dewar and Roya Khosravi-Far
19 Apoptosis in Prostate Cancer ............................... 293
Zongwei Wang, Rongbin Ge and Aria F. Olumi
20 Apoptosis and Colorectal Cancer ............................ 311
Shirish G. Prabhudesai, Gretta Roberts and Paul Ziprin
IV. Cardiovascular and Pulmonary Tissue
21 Apoptosis and Vascular Disease ............................. 327
Vyacheslav A. Korshunov
22 Apoptosis in Coronary Artery Disease and Reperfusion
Injury: Detection, Non-cardiomyocytes and Therapeutic
Strategies ................................................. 341
D. Tousoulis, A. Briasoulis, C. Antoniades and
C. Stefanadis
23 Potassium Channels and Apoptosis: Application to
Pulmonary Vascular Disease ................................. 357
Amy L. Firth, Amanda White and Jason X-J. Yuan
24 Molecular Regulation of Apoptosis Signaling Pathways in
Heart ...................................................... 373
Rimpy Dhingra, James Shaw and Lorrie A. Kirshenbaum
25 Potential Exercise Mitigation and Regulation of
Age-induced Apoptosis and Remodeling in the Heart .......... 389
John M. Lawler and Hyo-Bum Kwak
26 Apoptosis in Asthma ........................................ 405
Fernando Maria de Benedictis, Diletta de Benedictis and
Fabrizio Spinozzi
27 Apoptosis in Lung Diseases ................................. 421
Kazuyoshi Kuwano, Katsutoshi Nakayama and Jun Araya
V. Neuronal Tissues
28 Apoptotic Mechanisms Involved in Neurological Disorders .... 439
Anna Maria Colangelo and Lilia Alberghina
29 Apoptosis Signaling Pathways, Neuronal Death and
Epilepsy ................................................... 457
David C. Henshall
30 Apoptotic Mechanisms in Multiple Sclerosis: Diagnostic
and Therapeutic Opportunities .............................. 473
Andrea L.O. Hebb, Craig S. Moore, Virender Bhan and George
S. Robertson
VI. Immunologic and Infectious Aspects
31 Neutrophil Apoptosis and Its Involvement in
Inflammation and Infection ................................. 489
Fabien Loison and Hongbo R. Luo
32 Apoptosis in HIV/AIDS ...................................... 507
Andrea Cossarizza
33 Apoptosis in Immunosenescence .............................. 521
Lia Ginaldi and Massimo De Martinis
34 Apoptosis in Autoimmunity .................................. 535
Eleni Maniati, Nicola J. Rogers and Bernard J. Morley
35 Apoptosis in Lupus ......................................... 551
Kerstin Sarter, Connie Schulze, Christina Janko,
Christine Schorn, Luis Munoz and Martin Herrmann
VII Inhibitors
36 The Bax Inhibitor-1 (BI-1) Family in Apoptosis ............. 567
Kerstin Reimers and Peter M. Vogt
37 Targeting Inhibitor of Apoptosis (IAP) Proteins in
Cancer ..................................................... 583
Eugene Varfolomeev and Domagoj Vucic
VIII Methods
38 Morphological and Cytochemical Methods for the
Identification of Cell Death by Apoptosis .................. 603
Douglas J. Taatjes, Marilyn P. Wadsworth and Burton
E. Sobel
39 Quantification of Apoptosis ................................ 621
Glenda Gobe and Clay Winterford
40 Proteomic Screening in Apoptosis ........................... 635
Gregory Tufo, Cécile Martel, Gwenaёl Jan and Catherine
Brenner
Index ......................................................... 649
About the Editor .............................................. 655
Color Plate Section ........................................... 657
|
