1. THE DEVELOPMENT OF THE DROSOPHILA LARVAL BRAIN ............... 1
Volker Hartenstein, Shana Spindler, Wayne Pereanu
and Siaumin Fung
Abstract ..................................................... 1
Synopsis of the Phases and Elements of Drosophila Brain
Development .................................................. 1
Progenitors of the Drosophila Brain: Neuroblasts and
Ganglion Mother Cells ........................................ 3
The Generic Cell Types of the Drosophila Brain ............... 8
Neuroanatomy of the Developing Drosophila Brain:
The Systems of Lineages, Tracts and Compartments ............ 17
Outlook ..................................................... 29
2. ANTEROPOSTERIOR REGIONALIZATION OF THE BRAIN:
GENETIC AND COMPARATIVE ASPECTS ............................. 32
Robert Lichtneckert and Heinrich Reichert
Abstract .................................................... 32
Introduction ................................................ 32
The Cephalic Gap Genes Otd/Otx and Ems/Emx Control
Anterior Brain Development .................................. 34
The Hox Genes Pattern the Posterior Brain ................... 36
Evidence for a Tripartite Organization of the Brain ......... 37
3. DORSOVENTRAL PATTERNING OF THE BRAIN:
A COMPARATIVE APPROACH ...................................... 42
Rolf Urbach and Gerhard M.Technau
Abstract .................................................... 42
Introduction ................................................ 42
DV Patterning of the Truncal Part of the CNS in
Drosophila and Vertebrates .................................. 45
DV Patterning of the Brain in Drosophila .................... 48
A Comparison with DV Regionalization of the Vertebrate
Telencephalon ............................................... 52
Conclusions ................................................. 53
4. DISSECTION OF THE EMBRYONIC BRAIN USING
PHOTOACTIVATED GENE EXPRESSION .............................. 57
Jonathan Minden
Abstract .................................................... 57
Introduction ................................................ 57
Procephalic Blastoderm Fate Map ............................. 58
Brain-Forming Mitotic Domains Populate Distinct
Brain Regions ............................................... 58
Conclusion .................................................. 67
5. DESIGN OF THE LARVAL CHEMOSENSORY SYSTEM .................... 69
Reinhard F.Stocker
Abstract .................................................... 69
Introduction ................................................ 69
Chemosensory Organs of the Larval Head ...................... 70
Olfactory System ............................................ 71
Gustatory System ............................................ 77
The Drosophila Larva as a Model for Smell and Taste ......... 78
6. DEVELOPMENT OF THE DROSOPHILA OLFACTORY SYSTEM .............. 82
Veronica Rodrigues and Thomas Hummel
Abstract .................................................... 82
Introduction ................................................ 82
Organization of the Drosophila Adult Olfactory System ....... 84
Specification of the Olfactory Sense Organs ................. 84
Olfactory Lineages Revisited ................................ 87
Origin of GUal Cells ........................................ 89
Development of ORN Connectivity ............................. 89
Olfactory Map Organization .................................. 90
Cellular and Molecular Mechanisms of ORN Wiring
Specificity ................................................. 91
Specification of Projection Neurons ......................... 92
Development of PN Dendrites ................................. 95
Concluding Remarks .......................................... 96
7. THE OLFACTORY SENSORY MAP IN DROSOPHILA .................... 102
Philippe P.Laissue and Leslie B.Vosshall
Abstract ................................................... 102
Introduction ............................................... 102
Olfactory Organs and Olfactory Sensory Neurons of
Drosophila ................................................. 103
Odorant Receptor Gene Expression ........................... 104
Ligand Tuning Profiles ..................................... 105
A Receptor-Based Map of Glomerular Projections ............. 108
Sexual Dimorphism in the Drosophila Olfactory System Ill
Concluding Remarks ......................................... 112
8. OPTIC LOBE DEVELOPMENT ..................................... 115
Karl-Friedrich Fischbach and Peter Robin Hiesinger
Abstract ................................................... 115
Introduction ............................................... 115
The Adult Visual System Is Organized into Parallel
Visuotoptic Functional Pathways ............................ 116
Lamina Development ......................................... 120
Medulla and Lobula Complex Development ..................... 127
Concluding Remarks ......................................... 131
9. CLONAL UNIT ARCHITECTURE OF THE ADULT FLY BRAIN ............ 137
Kei Ito and Takeshi Awasaki
Abstract ................................................... 137
Introduction ............................................... 137
Structure of the Adult Brain ............................... 137
Techniques for Visualising Clonally Related Progeny ........ 139
Clonal Unit Architecture in the Adult Brain ................ 147
Formation of the Clonal Units During Development ........... 150
Functional Importance of the Clonal Units .................. 154
Conclusion ................................................. 156
INDEX ......................................................... 159
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