Preface ......................................................... v
Contributors ................................................... xv
Part I The Pituitary Gland
Introduction ................................................. 3
Pamela U. Freda
1. Pituitary Apoplexy ........................................... 9
Steven Jon Russell and Karen Klahr Miller
2. When and How to Stop Cabergoline Treatment in
Microprolactinomas .......................................... 19
Annamaria Colao
3. Cushing's Disease ........................................... 27
Kawaljeet Kaur and James W. Findling
Part II Thyroid Overactivity
Introduction ................................................ 37
David S. Cooper
4. Amiodarone-Induced Hyperthyroidism .......................... 41
Paul Aoun and David S. Cooper
5. Interferon-Induced Hyperthyroidism .......................... 49
Paul Aoun and David S. Cooper
6. Subclinical Hyperthyroidism Due to a Multinodular Thyroid ... 61
Paul Aoun and David S. Cooper
7. Subacute (De Quervain's) Thyroiditis ........................ 67
Paul Aoun and David S. Cooper
Part III Thyroid Underactivity
Introduction ................................................ 75
Anthony P.Weetman
8. Amiodarone-Induced Hypothyroidism ........................... 77
Ramzi Ajjan
9. Autoimmune Hypothyroidism with Persistent Elevation of
TSH ......................................................... 85
Amit Allahabadia
10.Hashimoto's Thyroiditis and Type 1 Diabetes ................. 93
Mark P.J. Vanderpump
Part IV Thyroid Cancer
Introduction ............................................... 103
Kenneth D. Burman
11.Papillary Thyroid Cancer ................................... 109
Nicole Ehrhardt and Victor Bernet
12.Metastatic Papillary Thyroid Cancer ........................ 121
Henry B. Burch
13.Medullary Thyroid Cancer ................................... 127
Jacqueline Jonklaas
14.Follicular Thyroid Carcinoma with Pulmonary and Osseous
Metastases ................................................. 139
Jason A. Wexler and Kenneth D.Burman
Part V Adrenal
15.Adrenal Insufficiency ...................................... 155
Lynn Loriaux
16.Cushing's Syndrome ......................................... 159
Lynn Loriaux
17.An Incidentally Discovered Adrenal Mass .................... 163
Lynn Loriaux
Part VI Hyperparathyroidism
Introduction ............................................... 169
Simon H.S. Pearce
18.Differentiation of Primary Hyperparathyroidism
for Familial Benign Hypocalciuric Hypercalcemia ............ 179
Ebaa Al Ozairi
19.Management and Investigation of Acute Hypercalcemia ........ 183
Suresh Vaikkakara, Chankramath S.Arun, and
R.Andrew James
20.Evaluation of Complex Primary Hyperparathyroidism .......... 187
Ее Lin Lim and Simon H.S. Pearce
21.Evaluation of Hypercalcemia in Infancy ..................... 191
Reena Thomas, Murthy Korada, and Timothy D. Cheetham
Part VII Metabolic Bone Diseases
Introduction ............................................... 197
Mone Zaidi
22.Osteoporosis Due to Hormonal Withdrawal: Common
Mistakes ................................................... 203
Mone Zaidi and Michael Pazianas
23.Osteomalacia: A Cause of Bisphosphonate Failure ............ 209
Michael Pazianas and Mone Zaidi
24.Unusual Manifestations of Paget's Disease of Bone .......... 215
Mone Zaidi and Michael Pazianas
25.Solid Organ Transplantation, Chronic Renal Impairment,
and Skeletal Complications ................................. 223
Michael Pazianas and Mone Zaidi
Part VIII Endocrine Disorders of Males
Introduction ............................................... 231
Stephen J. Winters and Sathya Krishnasamy
26.Congenital Isolated Hypogonadotropic Hypogonadism .......... 233
Stephen J. Winters and Sathya Krishnasamy
27.Klinefelter Syndrome ....................................... 241
Stephen J. Winters and Sathya Krishnasamy
28.Low Testosterone in Obesity and Type 2 Diabetes ............ 253
Stephen J. Winters and Sathya Krishnasamy
Part IX Female Reproduction
Introduction ............................................... 263
Janet E. Hall
29.Central Hypogonadism ....................................... 273
Maria A. Yialamas
30.Premature Ovarian Failure .................................. 279
Corrine K. Welt
31.Oligomenorrhea and Hyperandrogenemia ....................... 285
Sabrina Gill
Part X Pregnancy
Introduction ............................................... 295
Alex Stagnaro-Green
32.Hypertension in Pregnancy and Women with Child-Bearing
Potential .................................................. 299
Lawrence R. Krakoff
33.Hashimoto's Hypothyroidism During Pregnancy ................ 305
Susan J. Mandel
34.Type I Diabetes Mellitus During Pregnancy .................. 309
Carol Levy and Gal Omry
Part XI Type 1 Diabetes
Introduction ............................................... 321
Ake Lemmark
35.Type 1 Diabetes Onset with Ketoacidosis and Suspected
Cerebral Edema ............................................. 327
Helena E.Larsson, Sten-A Ivarsson, and Ake Lernmark
36.En Passant Diagnosis of Type 1 Diabetes in Infancy ......... 331
Helena E.Larsson, Sten-A Ivarsson, and Ake Lernmark
37.Type 1 Diabetes and Comorbidity of Addison's Disease ....... 337
Helena E. Larsson, Sten-A. Ivarsson, and Ake Lernmark
Part XII Type 2 Diabetes
Introduction ............................................... 343
Barry J. Goldstein
38.Exenatide in Type 2 Diabetes: Indications and
Initiation ................................................. 347
Vanita Treat and Serge Jabbour
39.Insulin Therapy in the Management of Diabetes
Mellitus Type 2 ............................................ 353
Kevin Furlong and Intekhab Ahmed
40.Treatment of Type 2 Diabetes Mellitus with Oral Agents ..... 359
Jeremy J. Flood and Jeffrey L. Miller
Part XIII Lipid Abnormalities
Introduction ............................................... 369
Neil J. Stone
41 Combination Drug Therapy in a Case of Severe
Hypercholesterolemia ....................................... 371
Conrad B. Blum
42 A Young Man with Abdominal Pain and Very High
Triglycerides: The Chylomicronemia Syndrome ................ 379
Molly С. Carr
43.Roughly Equivalent Lipids in a Middle-Aged Obese Man
at Risk for Coronary Disease ............................... 387
Stephen R. Crespin
Part XIV Obesity and the Metabolic Syndrome
Introduction ............................................... 395
Robert T. Yanagisawa and Derek LeRoith
44.Metabolic Syndrome ......................................... 399
Robert T. Yanagisawa and Derek LeRoith
45.Polycystic Ovarian Syndrome ................................ 407
Michael Magnotti and Walter Futterweit
46.Bariatric Surgery .......................................... 417
Robert T. Yanagisawa, Daniel Herron, and Derek
LeRoith
Part XV Puberty
Introduction ............................................... 427
Donald Zimmerman
47.Amenorrhea ................................................. 433
Liuska Pesce and Donald Zimmerman
48.Early Puberty and Hyperthyroidism .......................... 437
Liuska Pesce and Donald Zimmerman
49.Hypothalamic Hamartoma ..................................... 445
Liuska Pesce and Donald Zimmerman
50.Leydig Cell Adenoma ........................................ 453
Courtney Finlayson, Reema Habiloy, and Donald
Zimmerman
51.Prolactinoma ............................................... 459
Jami Josef son and Donald Zimmerman
52.lurner Syndrome ............................................ 465
Jami Josefson and Donald Zimmerman
Part XVI Instructive Rarities
Introduction ............................................... 473
Jeffrey I. Mechanick
53.Hypothalamic Damage and Obesity ............................ 475
Lalita Khaodhiar and Caroline M.Apovian
54.Systemic Mastocytosis ...................................... 483
Michael Kleerekoper and Luis Afonso
55.Testosteronoma ............................................. 489
Kimberley E. Steele and Martha A. Zeiger
Index ......................................................... 499
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