A Personal Journey of Discovery: Developing Technology and
Changing Biology
Lee Hood ..................................................... 1
Spectroscopic and Statistical Techniques for Information
Recovery in Metabonomics and Metabolomics
John C.Lindon and Jeremy K.Nicholson ........................ 45
Mass Spectrometry for Rapid Characterization of Microorganisms
Plamen A.Demirev and Catherine Fenselau ..................... 71
Scanning Electrochemical Microscopy
Shigeru Amemiya, Allen J.Bard, Fu-Ren F.Fan,
Michael V.Mirkin, and Patrick R.Unwin ....................... 95
Novel Detection Schemes of Nuclear Magnetic Resonance and
Magnetic Resonance Imaging: Applications from Analytical
Chemistry to Molecular Sensors
Elad Harel, Leif Schröder, and Shoujun Xu ............. 133
Chemical Cytometry: Fluorescence-Based Single-Cell Analysis
Daniella Cohen, Jane A.Dickerson, Colin D.Whitmore,
Emily H.Turner, Monica M.Palcic, Ole Hindsgaul, and
Norman J.Dovichi ........................................... 165
Chemical Analysis of Single Cells
Laura M.Borland, Sumith Kottegoda, K.Scott Phillips,
and Nancy L.Allbritton ..................................... 191
Ion Chemistry in the Interstellar Medium
Theodore P.Snow and Veronica M.Bierbaum .................... 229
Plasma Diagnostics for Unraveling Process Chemistry
Joshua M.Stillahn, Kristina J.Trevino,
and Ellen R.Fisher ......................................... 261
Biomolecule Analysis by Ion Mobility Spectrometry
Brian C.Bohrer, Samuel I.Merenhloom, Stormy L.Koeniger,
Amy E.Hilderbrand, and David E.Clemmer ..................... 293
In Vitro Electrochemistry of Biological Systems
Kelly L.Adams, Maja Puchades, and Andrew G.Ewing ........... 329
Current Applications of Liquid Chromatography/Mass
Spectrometry in Pharmaceutical Discovery After a Decade of
Innovation
Bradley L.Ackermann, Michael J.Berna, James A.Eckstein,
Lee W.Ott, and Ajai К.Chaudhary ............................ 357
Optical Probes for Molecular Processes in Live Cells
Yoshio Umezawa ............................................. 397
Cell Culture Models in Microfluidic Systems
Ivar Meyvantsson and David J.Beebe ......................... 423
Peptides in the Brain: Mass Spectrometry-Based Measurement
Approaches and Challenges
Lingjun Li and Jonathan V.Sweedler ......................... 451
Analysis of Atmospheric Aerosols
Kimberly A.Prather, Courtney D.Hatch,
and Vicki H.Grassian ........................................ 485
Multiplexed Spectroscopic Detections
Kyle D.Bake and David R.Walt ............................... 515
Terrestrial Analysis of the Organic Component of Comet Dust
Scott A.Sandford ........................................... 549
High-Resolution Mass Spectrometers
Alan G. Marshall and Christopher L. Hendrickson ............ 579
Surface-Enhanced Raman Spectroscopy
Paul L.Stiles, Jon A.Dieringer, Nilam C.Shah, and
Richard P.Van Duyne ........................................ 601
Time-Resolved Microdialysis for In Vivo Neurochemical
Measurements and Other Applications
Kristin N. Schultz and Robert T. Kennedy ................... 627
Applications of Ultrafast Lasers for Optical Measurements
in Combusting Flows
James R.Gord, Terrence R.Meyer, and Sukesh Roy ............. 663
Matrix-Assisted Laser Desorption/Ionization Imaging Mass
Spectrometry for the Investigation of Proteins and Peptides
Kristin E.Burnum, Sara L.Frappier, and
Richard M.Caprioli ......................................... 689
Formation and Characterization of Organic Monolayers on
Semiconductor Surfaces
Robert J.Hamers ............................................ 707
Nanoscopic Porous Sensors
John J.Kasianowicz, Joseph W.F.Robertson, Elaine
R.Chan, Joseph E.Reiner, and Vincent M.Stanford ............ 737
Combining Self-Assembled Monolayers and Mass Spectrometry
for Applications in Biochips
Zachary A.Gurard-Levin and Milan Mrksich ................... 767
Liposomes: Technologies and Analytical Applications
Aldo Jesorka and Owe Orwar ................................. 801
Fundamentals of Protein Separations: 50 Years of Nanotechnology,
and Growing
David A.Egas and Mary J.Wirth .............................. 833
Functional and Spectroscopic Measurements with Scanning
Tunneling Microscopy
Amanda M.Moore and Paul S.Weiss ............................ 857
Coherent Anti-Stokes Raman Scattering Microscopy: Chemical
Imaging for Biology and Medicine
Conor L.Evans and X.Sunney Xie ............................. 883
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