Applications of vibrational spectroscopy in pharmaceutical research development (Chichester, 2007). - ОГЛАВЛЕНИЕ / CONTENTS
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ОбложкаApplications of vibrational spectroscopy in pharmaceutical research development / ed. by Pivonka D.E., Chalmers J.M., Griffiths P.R. - Chichester: Wiley, 2007. - 372 p. - ISBN 978-0-470-87087-7
 

Оглавление / Contents
 
List of Contributors ........................................... xi

Part One: Introduction

Introduction to Vibrational Spectroscopy ........................ 3
   Peter R. Griffiths

Part Two: Drug Discovery

Sampling Techniques and Fiber-Optic Probes ..................... 19
   John M. Chalmers and Peter R. Griffiths

Vibrational Spectroscopy in the Discovery Phase Component
of Pharmaceutical Research ..................................... 51
   Don E. Pivonka

Applications of Vibrational Spectroscopy to Combinatorial
Chemistry ...................................................... 75
   Don E. Pivonka

Vibrational Spectroscopic Analysis for the Determination of
Structure-Activity Relationships (SARs)in Molecular Binding ... 109
   Don E. Pivonka and Isao Noda

Applications of Vibrational Optical Activity in the
Pharmaceutical Industry ....................................... 129
   Laurence A. Nafie and Rina K. Dukor

Characterization and Optimization of Chemical Synthesis
Using Real-Time Vibrational Spectroscopy ...................... 155
   Fadi Homsi, Paul Barrett, Jian Wang and Roel Ferwerda

Part Three: Drug Development

Infrared and Raman Spectroscopy for Process Development ....... 185
   George Zhou, Robert Guenard and Zhihong Ge

The Analysis of Pharmaceutical Substances and Formulated
Products by Vibrational Spectroscopy .......................... 213
   Don Clark and Alexander Pysik

Raman Analysis of Pharmaceuticals ............................. 239
   David E. Bugay, Jan-Olav Henck, Michael L. Longmire and
   Fiona C. Thorley

Vibrational Spectroscopy of Solid-State Forms -
Introduction, Principles and Overview ......................... 263
   Terry L. Threlfall and John M. Chalmers

Vibrational Spectroscopy of Solid-State Forms -
Applications and Examples ..................................... 293
   David H. Igo and Pingyun Chen

Pharmaceutical Applications of Chemical Mapping and Imaging ... 309
   Don Clark, Mark Henson, Fred LaPlant, Slobodan Sasic and
   Lin Zhang

Terahertz Spectroscopy for Pharmaceutical Applications ........ 337
   Mike Claybourn, Husheng Yang, Lubomir Gradinarsky,
   Jonas Johansson and Staffan Folestad

Part Four: Conclusions

History, Trends and Prognostications .......................... 353
   Peter R. Griffiths, John M. Chalmers and Don E. Pivonka

Index ......................................................... 363


 
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