Поступления иностранных книг в библиотеки ННЦ в 2003 г.
Институт биоорганической химии |  |
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The role of DNA damage and repair in cell aging / Ed.: Gilchrest B.A., Bohr V.A.. - Amsterdam et al.: Elsevier, 2001. - VII, 257 p. : ill. - (Advances in cell aging a. gerontology; Vol. 4). - Роль повреждения и восстановления ДНК в старении клеток.
Оглавление
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- This book is an excellent single source of information for anyone interested in DNA repair, mechanisms of aging, or certainly their intersection. Students will gain a general appreciation of these fields, but even the most senior investigators will benefit from the detailed coverage of rapidly advancing areas.As part of a series entitled "Advances in Cell Aging and Gerontology," this volume summarizes seminal recent discoveries such as the molecular basis for Werner syndrome (a mutant DNA helicase), the complementary roles of telomere shortening and telomerase activity in cell senescence versus immortalization, the role of apoptosis in the homeostasis of aging tissue, and the existence of an inducible SOS-like response in mammalian cells that minimizes DNA damage from repeatedly encountered injurious environmental agents. Insights into the relationship between cellular aging and age-associated diseases, particularly malignancies, are also provided in several chapters.
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